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. 2015 Jun 10;6(27):24448–24462. doi: 10.18632/oncotarget.4423

Figure 1. miR-99b-5p was down-regulated in liver metastases compared with the primary colorectal cancer.

Figure 1

A. Affymetrix Human Transcriptome Array 2.0 microarray (Invitrogen, Carlsbad, CA, USA) screened the differential expression of miRNA between primary tumor and liver metastases in two pairs of fresh tissue. B. The expression of miR-99b-5p was reduced in liver metastases compared with primary tumor in 48 pairs; P = 0.007 (paired t-test). C. The expression of miR-99b-5p was reduced in colorectal cancer patients with liver metastases compared with those without liver metastases; P = 0.028 (non-paired t-test). Abbreviation: met, metastases.