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. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Acta Biomater. 2015 Nov 18;30:212–221. doi: 10.1016/j.actbio.2015.11.024

Figure 2.

Figure 2

Polarized optical microscopy illustrates the similarities in the orientations of the collagen fibers in native articular cartilage and woven collagen scaffold. Schematic depiction of arcade like structures formed by the changing orientation of collagen fibers in the articular cartilage [41–44]. Collagen fibers are oriented parallel to the surface of cartilage in the superficial region and in deeper zones the orientation changes to vertical orientation (a), this variation of the orientation of collagen fibers are manifested in blue in the superficial region and orange color in deep zone (a) as well as in woven scaffold which mimic the collagen fiber orientation of the native articular cartilage (b). (Scale bars: 500 μm).