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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Osteoarthritis Cartilage. 2015 Aug 6;24(1):178–187. doi: 10.1016/j.joca.2015.07.022

Fig. 6.

Fig. 6

The osteoclast numbers in the mandibular condylar subchondral bone in the control and UAC mice. (A) TRAP staining in the mouse mandibular condylar subchondral bone. Bars = 200 μm in the low-magnification images and Bars = 50 μm in the high-magnification images. (B) Quantitative analysis of TRAP-positive osteoclasts (n = 6). P values: 2w: P-values between groups with * are less than 0.001; 4w: CON + Saline vs UAC + Saline and UAC + SrCl2: P < 0.001 and P = 0.032; UAC + Saline vs UAC + SrCl2 and UAC + NBD peptide: both P < 0.001. (C) mRNA expressing levels of rank in condylar subchondral bone were shown (n = 3). P values: 2w: CON + Saline vs UAC + Saline, UAC + SrCl2 and UAC + NBD peptide: P < 0.001, P = 0.005 and P = 0.015; UAC + Saline vs UAC + SrCl2 and UAC + NBD peptide: P = 0.002 and P = 0.001; 4w: CON + Saline vs UAC + Saline: P = 0.001; UAC + Saline vs UAC + SrCl2 and UAC + NBD peptide: P = 0.002 and P < 0.001. Data are expressed as means and 95% confidence intervals (CIs); * indicates statistically significant differences between groups.