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. Author manuscript; available in PMC: 2016 Dec 5.
Published in final edited form as: Chem Biol Interact. 2015 Sep 30;242:99–106. doi: 10.1016/j.cbi.2015.09.025

Fig. 1. Cardiac hypertrophy and ER stress response in mice following TAC.

Fig. 1

(A) The diagram of transverse aortic constriction (TAC) in mouse. (B) The representative autopsy pictures of aortic rupture and congestive heart failure within the 4 weeks of TAC. (C) Representative autopsy pictures of the normal heart and hypertrophic heart induced by pressure overload for 4 weeks and the corresponding quantitative analysis of heart weight over body weight ratio. *P<0.05 vs. Sham; n=8 in each group. (D) Western blots and quantitative analysis of ER stress response markers (GRP78, CHOP and p-PERK) in the whole heart homogenates of mice in designated time points after TAC. *P<0.05 vs. Sham; n=3.