Table 4.
Outcomes among patients deemed allergic
| Variable | Metoclopramide + diphenhydramine | Metoclopramide + placebo | Difference (95%CI) |
|---|---|---|---|
| Improvement in 0–10 pain score between baseline and one hour | 3.8 (n=15) | 3.7 (n=12)* | 0.1 (−2.1, 2.3) |
| Requirement of Rescue medication | 6/15 (40%) | 3/14 (21%) | 19% (−14, 51%) |
| Sustained headache freedom1 | 3/15 (20%) | 1/13 (8%) | 12% (−13, 37%) |
| Want same med again2 | 14/15 (93%) | 7/13 (54%) | 39% (10, 69%) |
*
2 patients did not provide an answer to this question
1
Achieved a headache level of “none” in the ED and maintained a level of “none” without the use of rescue medication for 48 hours. Patients who required rescue medication were considered outcome failures.
2
At the 48 hour follow-up telephone call patients were asked if they wished to receive the same medication during a subsequent migraine visit to the ED.