Fig. 1.
Estrogen-mediated neuroprotection is initiated at the membrane level in mesencephalic cultures. Mouse mesencephalic cultures were pre-treated with 17β-estradiol, or E2-BSA prior to the addition of MPP+ (10μM). Results are presented as number of TH-ir cells, percent of control and represent the mean SEM of three experiments. ***p<0.001 compared to vehicle-treated control, ###p<0.001 and ##p<0.01 compared to MPP+ treatment.