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. 2015 Jul 2;8(1):12–21. doi: 10.4168/aair.2016.8.1.12

Table. Determinants of FeNO levels in children.

Factors Effect on FeNO levels
Age Age-dependent increase10,12,13,14,15
Gender Boys >Girls13,15,19
Race/ethnicity Asians higher than whites10,12,13,19
Hispanic children higher than non-Hispanic white children13
Height Rise by height gained12
Nitrate containing food Increase21
Caffeine Conflicting results24,25
Respiratory tract infection Unclear26,27
Circadian rhythm Unclear10
Exercise Transient reduction23
Spirometry, bronchial challenge test, sputum induction Transient reduction30,31
Smoking
 Active Reduction22,55
 Passive Transient reduction56
Atopy Increase17,32,33,34,38
Outdoor air pollution
 Ozone, NO2, PM2.5, PM10, elemental carbon Increase by acute and chronic exposure43,44,45,46
Indoor air pollution
 Electric baseboard heating Increase49,50,51
 Woodstoves, candles, gas cooker Not associated52
 Polyvinyl chloride material Unclear53,54
Medication
 Inhaled or systemic corticosteroid Reduction28
 Leukotriene receptor antagonist Reduction29