Table II.
Primary and secondary outcomes in two groups
Variable | Group A (400 IU Vit D) | Group B (50,000 IU Vit D every 2 weeks) | p-value |
---|---|---|---|
25 (OH) D3 of pregnant women at delivery time (ng/ml) (Mean±SD) | 27.2±18.8 | 37.9±19.8 | 0.001 |
OGTT Results at 24-28 weeks | |||
Number Fasting blood glucose (mg/dl) (Mean±SD) 1-h OGTT 2-h OGTT 3-h OGTT |
246 86.4±12.9 164.4±35.6 137.3±33.9 108.6±31.2 |
224 82±11.9 153.4±33.7 127.1±30.6 94.1±24.4 |
0.004 0.022 0.023 0.001 |
GDM (%) | 13.4 | 6.7 | 0.01 |
Maternal outcomes | |||
Number Gestational hypertension (%) Preeclampsia (%) Preterm delivery (%) |
203 0.7 2 4.2 |
186 1.3 3.9 5.2 |
0.57 0.33 0.58 |
Neonatal outcomes ( Mean±SD) | |||
Number Birth length (cm) Birth weight, (g) Head circumference(cm) Apgar (minute1) Apgar (minute 5) |
203 50.22±5.4 3125.57±434.9 34.31±2.8 9.7±0.7 9.8±0.5 |
186 50.39±2.1 3088.72±481.21 34.35±2.2 9.83±0.6 9.9±0.2 |
0.7 0.43 0.88 017 0.17 |
25( OH) D3 of cord blood( ng/ml) (Mean±SD) | 29.7±19 | 37.9±18 | 0.005 |
Neonatal complication (%) | |||
Low birth weight Macrosomia Hypoglycemia Respiratory distress |
4 1.5 4.1 1 |
5.9 1.6 1.2 1.2 |
0.25 0.61 0.07 0.67 |
Chi-Square test and Student’s t- test were used to compare variables between two groups.
25 OH D3: 25-hydroxy vitamin D; OGTT: oral glucose tolerance test; GDM: Gestational diabetes mellitus