Skip to main content
. 2015 Nov 25;8(4):816–835. doi: 10.3390/ph8040816

Table 1.

Fatty acid signaling molecules with known functions in the various microorganisms.

Compound New Nomenclature Structure Bacterial Species Function Reference
cis-11-Methyl-2-dodecenoic acid (DSF) 11-Me-C122 graphic file with name pharmaceuticals-08-00816-i001.jpg Xanthomonas campestris, Xanthomonas oryzae, Stenotrophomonas maltophilia, Burkholderia multivorans Virulence, biofilm formation, floc disaggregation, microcolony formation, tolerance to antibiotics, detoxification, hyphal growth inhibition [96,97,98,99,104,105]
cis-2-Dodecenoic acid (BDSF) C122 graphic file with name pharmaceuticals-08-00816-i002.jpg Burkholderia cenocepacia, Burkholderia lata Burkholderia stabilis Burkholderia vietnamiensis Burkholderia dolorosa Burkholderia ambifaria Burkholderia anthina Burkholderia pyrrocinia B. multivorans, X. oryzae Virulence, hyphal growth inhibition [97,104,106,107]
cis-2-Decenoic acid (cis-DA) C102 graphic file with name pharmaceuticals-08-00816-i003.jpg Pseudomonas aeruginosa Biofilm formation, biofilm dispersion, persister cell formation, persister cell awakening, tolerance to antimicrobials. [19,65,108,109,110]
cis-2-Tetradecenoic acid C142 graphic file with name pharmaceuticals-08-00816-i004.jpg Xylella fastidiosa Virulence and aggregation [100]
trans-2-Decenoic acid (SDSF) C102t graphic file with name pharmaceuticals-08-00816-i005.jpg Streptococcus mutans Hyphal growth inhibition [111]
cis-11-Methyldodeca-2,5-dienoic acid (CDSF) 11-Me-C122,5 graphic file with name pharmaceuticals-08-00816-i006.jpg B. multivorans, B. stabilis B. anthina, B. pyrrocinia, X. oryzae Hyphal growth inhibition [97,104]
10-Methyldodecanoic acid 10-Me-C12 graphic file with name pharmaceuticals-08-00816-i007.jpg S. maltophilia Stress tolerance and antibiotic tolerance [105]
11-Methyldodecanoic acid 11-Me-C12 graphic file with name pharmaceuticals-08-00816-i008.jpg S. maltophilia Stress tolerance and antibiotic tolerance [105]
12-Methyltetradecanoic acid 12-Me-C14 graphic file with name pharmaceuticals-08-00816-i009.jpg Xylella fastidiosa Virulence, biofilm formation, motility [112,113]
3-Hydroxypalmitic acid 3OH-PAME graphic file with name pharmaceuticals-08-00816-i010.jpg Ralstonia solanacearum Virulence [114]
Farnesoic acid 3,7,11-Me-C122t,6t,1°t graphic file with name pharmaceuticals-08-00816-i011.jpg Candida albicans Inhibition of germ tube formation [115]