Table 2.
Mutations in the highly conserved TASNIKS and YCF motifs of domain 1 of ciliate eRF1s, which alter stop codon recognition specificity and constitute an important step in codon reassignment (adapted from [51]).
| TASNIKS motif | YCF motif | S70 | |
|---|---|---|---|
| Canonical codes | TASNIKS | YLCDNKF | Ser |
| Paramecium tetraurelia | EAASIKD | YFCDPQF | Ser |
| Loxodes striatus | RAQNIKS | FLCENTF | Ala |
| Oxytricha trifallax | AAQNIKS | YFCGGKF | Ser |
| Tetrahymena thermophila | KATNIKD | YFCDSKF | Ser |
| Stylonychia lemnae | AAQNIKS | YFCGGKF | Ser |
| Stylonychia mytilus | AAQNIKS | YFCGGKF | Ser |
| Euplotes octocarinatus/a | TAESIKS | YICDNKF | Ala |
| Euplotes octocarinatus/b | TAVNIKS | YICDNKF | Ala |
| Euplotes aediculatus/a | TAESIKS | YICDNKF | Ala |
| Euplotes aediculatus/b | TAVNIKS | YICDNKF | Ala |
| Blepharisma americanum | KSSNIKS | YICDNKF | Ala |
| Blepharisma japonica | KSSNIKS | YICDNKF | Ala |
| Blepharisma musculus | KSSNIKS | YICDNKF | Ala |