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(A) HINT domain of Drosophila melanogaster Hh precursor (PDB#, 1AT0); (B) conserved catalytic residues of the HINT domain; an (C) alignment of Hh HINT domain with self-splicing intein (PDB#, 2IN0). Figures rendered using PyMol (DeLano Scientific LLC, Palo Alto, CA, USA).
