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. 2015 Oct 14;7(4):2037–2053. doi: 10.3390/cancers7040875

Figure 5.

Figure 5

(A) Cholesterol targets soluble Hh ligand to cell membranes; (B) Proteins associate with Hh ligand via cholesterol; and (C) Micellization of the Hh ligand stabilized by hydrophobic interactions of the attached lipids.