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Mutation rates by subsite from TCGA. Subsites defined from the initial 279 patients in TCGA. Key frequently-mutated genes are highlighted. OC = oral cavity; OP = oropharynx; L = larynx.
| OC (n = 172) | OP (n = 33) | L (n = 72) | |
|---|---|---|---|
| HPV+ | 7.0% | 66.7% | 1.4% |
| TP53 | 75.6% | 27.3% | 88.9% |
| FAT1 | 26.2% | 12.1% | 19.4% |
| CDKN2A | 25.6% | 6.1% | 23.6% |
| PIK3CA | 17.4% | 30.3% | 25.0% |
| NOTCH1 | 21.5% | 6.1% | 18.1% |
