Table 2.
GLI1 regulatory kinases and their sites of phosphorylation on GLI1.
GLI1 Regulatory Kinases | ||
---|---|---|
Kinase | Residue | Activating or Inhibitory |
Protein Kinase A | Thr-374 | Inhibitory |
Protein Kinase A | Ser-640 | Inhibitory |
Ribosomal protein S6 kinase 1 | Ser-84 | Activating |
Atypical Protein Kinase C | Ser-243 | Activating |
Atypical Protein Kinase C | Thr-304 | Activating |
AMPK | Ser-102 | Inhibitory |
AMPK | Ser-408 | Inhibitory |
AMPK | Thr-1074 | Inhibitory |