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Minimum biofilm eradication concentrations (MBEC2h) and bactericidal NO doses of alkyl-modified G1 PAMAM dendrimers against S. mutans biofilms at pH 7.4 and 6.4.a
| pH = 7.4 |
pH = 6.4 |
|||
|---|---|---|---|---|
| MBEC2h (mg/mL) | NO Dose (μmol/mL) | MBEC2h (mg/mL) | NO Dose (μmol/mL) | |
| Propyl | >64 | >48 | ||
| Propyl-NO | 64 | 52.5 | 8 | 8.7 |
| Butyl | >64 | 48 | ||
| Butyl-NO | 48 | 46.6 | 8 | 7.8 |
| Hexyl | 8 | 8 | ||
| Hexyl-NO | 8 | 7.2 | 8 | 8.2 |
| Octyl | 2 | 2 | ||
| Octyl-NO | 2 | 1.8 | 2 | 2.1 |
| Dodecyl | 2 | 1 | ||
| Dodecyl-NO | 2 | 1.8 | 2 | 2.1 |
Results of n ≥ 3 pooled experiments.
