Table 13.
Yield for germline mutations In familial pancreatic cancer (FPC) kindreds without criteria for known genetic syndromesa
Mutation | Yield of testing | References |
---|---|---|
BRCA1 | 0 to 6% | (281,286) |
BRCA2 | 0 to 6% | (281,287,288) |
CDKN2A | 0 to 20% | (280,281,288) |
PALB2 | 0 to 5% | (281,285,288) |
ATM | 2.4% | (283) |
STK11 | 0% | (288) |
PALLD | 0% | (289,363) |
Unknown for Lynch syndrome, familial adenomatous polyposis (FAP), and Li–Fraumeni syndrome.