Table 1.
All ages combined | SLE cohort (N = 18,423)
|
Control cohort (N = 3,651,715)
|
||||||
---|---|---|---|---|---|---|---|---|
Cases | Total | Unadjusted incidence [95 % CI] | Age-adjusted incidence [95 % CI] | Cases | Total | Unadjusted incidence [95 % CI] | Age-adjusted incidence [95 % CI] | |
All | 416 | 18,423 | 2.26 [2.05–2.48] | 2.23 [1.94–2.55]a | 94,572 | 3,651,715 | 2.59 [2.57–2.61] | 2.14 [1.95–2.34]a |
Caucasians | 315 | 13,231 | 2.38 [2.13–2.66] | 2.41 [2.16–2.69] | 82,062 | 3,058,316 | 2.68 [2.66–2.70] | 2.54 [2.52–2.56] |
African Americans | 68 | 3839 | 1.77 [1.38–2.24] | 1.97 [1.55–2.50] | 8740 | 370,533 | 2.36 [2.31–2.41] | 2.18 [2.13–2.24] |
Others | 33 | 1353 | 2.44 [1.68–3.41] | 2.44 [1.71–3.47] | 3770 | 222,866 | 1.69 [1.64–1.75] | 1.60 [1.46–1.75] |
Age ≥65 years | ||||||||
All | 264 | 9795 | 2.70 [2.38–3.04] | 2.54 [2.14–3.01]a | 84,629 | 3,101,399 | 2.73 [2.71–2.75] | 2.54 [2.28–2.83]a |
Caucasians | 215 | 8079 | 2.66 [2.32–3.04] | 2.49 [2.18–2.84] | 74,763 | 2,654,412 | 2.82 [2.80–2.84] | 2.75 [2.73–2.77] |
African Americans | 27 | 1140 | 2.37 [1.57–3.43] | 2.18 [1.50–3.18] | 6686 | 261,264 | 2.56 [2.50–2.62] | 2.51 [2.45–2.57] |
Others | 22 | 576 | 3.82 [2.41–5.73] | 3.58 [2.33–5.51] | 3180 | 185,723 | 1.71 [1.65–1.77] | 1.69 [1.54–1.86] |
Age <65 years | ||||||||
All | 152 | 8628 | 1.76 [1.49–2.06] | 1.60 [1.35–1.90]a | 9943 | 550,316 | 1.81 [1.77–1.84] | 1.55 [1.47–1.64]a |
Caucasians | 100 | 5152 | 1.94 [1.58–2.36] | 1.60 [1.31–1.95] | 7299 | 403,904 | 1.81 [1.77–1.85] | 1.50 [1.45–1.55] |
African Americans | 41 | 2699 | 1.52 [1.09–2.06] | 1.46 [1.08–1.99] | 2054 | 109,269 | 1.88 [1.80–1.96] | 1.58 [1.50–1.67] |
Others | 11 | 777 | 1.42 [0.71–2.52] | 1.12 [0.60–2.08] | 590 | 37,143 | 1.59 [1.46–1.72] | 1.15 [0.93–1.41] |
Race adjusted