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. 2015 Dec 29;15:1025. doi: 10.1186/s12885-015-2039-6

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© Chai et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Effects of ibuprofen on prostasin expression. a & b the UROtsa cells were treated with ibuprofen for 24 h at different dosages as indicated. a RT-qPCR (n = 3). b western blotting (representative image from three experiments). c & d the UROtsa cells were treated with 2 mM ibuprofen for different time periods as indicated. c RT-qPCR (n = 3). d western blotting (representative image from three experiments). The numbers above each bar (a) & (c) indicate the fold change of the expression as compared to the DMSO control. One-way ANOVA and Tukey’s post hoc were used for data analysis, and p < 0.05 was considered statistically significant. The asterisk denotes p <0.05 between IBU treated and DMSO control cells