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. 2015 Dec 30;13:390. doi: 10.1186/s12967-015-0759-7

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© Friques et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Time-course of the effects of kefir administration on the endothelial dysfunction of SHR. Dose–response curves to acetylcholine-induced relaxations of aortic rings from SHR-kefir compared to the non-treated SHR and to the normotensive Wistar rats (a). The bar graphs show the maximum relaxation (b), the area under the curve (c) and the sensitivity (pEC₅₀, d) to acetylcholine. The values shown are the mean ± SEM. *p < 0.05 vs. Wistar group; ^#p < 0.05 vs. SHR (two-way ANOVA)