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Cardiac myocytes produce significantly more oxidants with age. A) Cells from old rats (24 months) produce ~45% more oxidants, as measured by DCFH fluorescence, than cells from young (3 months) rats. B) The rate of oxidant production is even more marked when oxidant production is normalized to the cellular rate of O2 consumption. Results are expressed as the mean ± SE of 3 experiments.
