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. Author manuscript; available in PMC: 2015 Dec 30.
Published in final edited form as: J Pineal Res. 2014 Feb 19;56(3):254–263. doi: 10.1111/jpi.12118

Fig. 3.

Fig. 3

Melatonin increases the amplitude of the 22 hr peak activity rhythm. Animals treated with melatonin for 3 wk in 22 hr T-cycles showed an increased amplitude of the 22 hr spontaneous activity rhythm as compared to 3 wk vehicle treatment under similar conditions. *P < 0.005 student t-test. Error bars represent S.E.M. Only animals with peak activity rhythms of 22 hr in the presence or absence of free-running activity rhythms during both stage 1 and stage 2 were included in the analysis. Veh, Vehicle; Mel, melatonin.