Table 3.

Adjusted^a coefficients (β) and (95% CI) in points on the MDI and PDI of the Bayley Scales of Infant Development per two-fold increase in manganese levels (AUC ⁵⁵Mn:⁴³Ca), CHAMACOS study.

Outcome	Prenatal Dentine				Postnatal Dentine
	N	β	(95% CI)	p-value	N	β	(95% CI)	p-value
MDI 6-months	177	−1.0	(−2.7, 0.6)	0.21	176	−0.8	(−1.4, −0.2)	0.01	#
PDI 6-months	180	−0.4	(−2.9, 2.1)	0.75	177	−0.7	(−1.6, 0.1)	0.10	#
MDI 12-months	187	−1.1	(−3.3, 1.1)	0.32	185	−0.9	(−1.8, −0.1)	0.03
PDI 12-months	187	2.1	(−1.3, 5.5)	0.22	185	−0.4	(−1.7, 0.9)	0.57
MDI 24-months	185	1.1	(−1.8, 4.0)	0.47	181	0.6	(−0.6, 1.7)	0.33
PDI 24-months	186	0.1	(−2.5, 2.6)	0.96	182	−0.4	(−1.4, 0.6)	0.44

^aAdjusted for child's age, sex, maternal education, maternal intelligence, psychometrician, location of assessment, household poverty and HOME score at the time of the assessment. Postnatal models also adjusted for prenatal Mn. Excluding outliers with studentized residuals > |3|.

^#Non-linear (p_GAM<0.05).