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PAS stainings of Yap-KO and control (Ctrl) mice at 12 weeks. (A,B) Ctrl kidney sections at low and high power. (C) Yap-KO mice with focal glomerulosclerosis and tubular dilatation and casts. (D) Yap-KO mouse with a lesion of focal segmental glomerulosclerosis. (E) Quantification of glomerular and tubular injury in 12-week-old mice. Scale bars, (A) and (C) 70 µm; (B) and (D) 50 µm.
