Table 2.
Inhibition of Flavivirus MTases by Compounds NSC 12155 and NSC 125910
| NSC 12155 | NSC 125910 | |||
|---|---|---|---|---|
| MTase | IC50 N7 (µM) |
IC50 2′-O (µM) |
IC50 N7 (µM) |
IC50 2′-O (µM) |
| DENV2 | 1.2 | 7.6 | 12.6 | 7.4 |
| DENV3 | 3.4 | 7.7 | 74.8 | 20.9 |
| YFV | 2.8 | 0.5 | 7.5 | 0.4 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.