Table 1. Descriptive, univariable, and multivariable analysis of patients diagnosed with symptomatic versus nonsymptomatic LGV CT infection among men who have sex with men, by demographic and behavioral characteristics, United Kingdom*.
| Patient characteristics |
No. (%) or median [IQR] |
|
Univariable analysis |
|
Multivariable analysis† |
|||||
| All CT |
Non-LGV CT |
LGV CT |
OR (95% CI) |
p value |
OR (95% CI) |
p value |
||||
| All patients |
713 (100) |
647 (90.7) |
66 (9.3) |
ND |
ND |
ND |
ND |
|||
| Clinic location, n = 713 | ||||||||||
| London | 563 (79.0) | 512 (79.1) | 51 (77.3) | 1 | 0.73 | |||||
| Manchester | 85 (11.9) | 75 (11.6) | 10 (15.2) | 1.34 (0.65–2.75) | ||||||
| Brighton | 42 (5.9) | 38 (5.9) | 4 (6.1) | 1.06 (0.36–3.08) | ||||||
| Glasgow‡ |
23 (3.2) |
22 (3.4) |
1 (1.5) |
|
|
|
|
|
|
|
| Infection site, n = 710 | ||||||||||
| Nonrectal | 221 (31.1) | 217 (33.7) | 4 (6.1) | 1 | 1 | |||||
| Rectal |
489 (68.9) |
427 (66.3) |
62 (93.9) |
|
7.83 (2.81–21.82) |
<0.001 |
|
10.08 (3.37–30.17) |
<0.001 |
|
| Multiple infection sites, n = 713 | ||||||||||
| No | 641 (89.9) | 581 (89.8) | 60 (90.9) | 1 | ||||||
| Yes |
72 (10.1) |
66 (10.2) |
6 (9.1) |
|
0.89 (0.37–2.15) |
0.8 |
|
|
|
|
| Symptoms present, n = 650 | ||||||||||
| No | 453 (69.7) | 438 (73.6) | 15 (27.3) | 1 | 1 | |||||
| Yes |
197 (30.3) |
157 (26.4) |
40 (72.7) |
|
7.93 (4.20–14.99) |
<0.001 |
|
13.33 (6.53–27.21) |
<0.001 |
|
| Age, y, n = 710 | 33 [27–42] | 33 [27–42] | 39 [33–46] | |||||||
| 18–24 | 108 (15.2) | 106 (16.5) | 2 (3.0) | 1 | 0.002 | |||||
| 25–34 | 276 (38.9) | 258 (40.1) | 18 (27.3) | 3.72 (0.85–16.31) | ||||||
| 35–44 | 192 (27.0) | 166 (25.8) | 26 (39.4) | 7.92 (1.84–34.15) | ||||||
|
>44 |
134 (18.9) |
114 (17.7) |
20 (30.3) |
|
9.11 (2.08–39.93) |
|
|
|
|
|
| Ethnicity, n = 603 | ||||||||||
| White | 480 (79.6) | 432 (79.3) | 48 (82.8) | 1 | 0.17 | |||||
| Black or Black British | 28 (4.6) | 27 (5) | 1 (1.7) | 0.33 (0.44–2.51) | ||||||
| Mixed | 27 (4.5) | 27 (5) | 0 | NP | ||||||
| Asian and Asian British | 21 (3.5) | 21 (3.9) | 0 | NP | ||||||
| Other ethnic groups | 23 (3.8) | 19 (3.5) | 4 (6.9) | 1.89 (0.62–5.80) | ||||||
| Unknown |
24 (4) |
19 (3.5) |
5 (8.6) |
|
2.37 (0.85–6.63) |
|
|
|
|
|
| HIV status, n = 603 | ||||||||||
| Negative | 367 (60.9) | 350 (64.2) | 17 (29.3) | 1 | 1 | |||||
| Positive |
236 (39.1) |
195 (35.8) |
41 (70.7) |
|
4.33 (2.40–7.82) |
<0.001 |
|
3.63 (1.80–7.32) |
<0.001 |
|
| No. sexual partners in previous 3 mo, n = 635 | ||||||||||
| No. partners | 3 [1–5] | 3 [1–5] | 3 [1–8] | |||||||
| 0–1 | 169 (26.6) | 153 (26.3) | 16 (29.6) | 1 | 0.26 | |||||
| 2–5 | 321 (50.6) | 299 (51.5) | 22 (40.7) | 0.66 (0.34–1.31) | ||||||
|
>6 |
145 (22.8) |
129 (22.2) |
16 (29.6) |
|
1.13 (0.54–2.36) |
|
|
|
|
|
| Concurrent sexually transmitted infection, n = 631 | ||||||||||
| No | 451 (71.5) | 406 (71) | 45 (76.3) | 1 | ||||||
| Yes |
180 (28.5) |
166 (29) |
14 (23.7) |
|
0.76 (0.41–1.42) |
0.39 |
|
|
|
|
| STI within previous 12 mo, n = 594 | ||||||||||
| No | 469 (79) | 435 (80.3) | 34 (65.4) | 1 | ||||||
| Yes | 125 (21) | 107 (19.7) | 18 (34.6) | 2.15 (1.17–3.96) | 0.01 | |||||
*n values indicate number of patients for which data were available in each category. CT, Chlamydia trachomatis; LGV, lymphogranuloma venereum; IQR, interquartile range; OR, odds ratio; ND, no data were available; NP, not performed. Blank cells indicate not applicable. †Multivariable analysis adjusted for age and location. ‡Glasgow patients were excluded from all univariable and multivariable analyses because they do not routinely report to the Genitourinary Medicine Clinic Activity Dataset.