Table 1. Summary of autoantigens identified by LC-MS/MS.
Gene Name | Protein denomination | UniProt Accession No. | Peptides Identified a | XCorr (z) b |
---|---|---|---|---|
HSPA8 | Heat shock cognate 71 kDa protein, a.k.a. HSP70-8 | P11142 | NQTAEKEEFEHQQK | 3.34 (3) |
RFDDAVVQSDM*K | 3.41 (2) | |||
M*KEIAEAYLGK | 3.94 (2) | |||
RFDDAVVQSDMK | 3.37 (2) | |||
NQVAM*NPTNTVFDAK | 5.19 (2) | |||
MKEIAEAYLGK | 3.35 (2) | |||
SQIHDIVLVGGSTR | 4.84 (2) | |||
HWPFM*VVNDAGRPK | 3.44 (3) | |||
NSLESYAFNM*K | 4.27 (2) | |||
MVNHFIAEFK | 2.92 (2) | |||
NQVAMNPTNTVFDAK | 4.83 (2) | |||
NSLESYAFNMK | 3.40 (2) | |||
SFYPEEVSSM*VLTK | 5.06 (2) | |||
TVTNAVVTVPAYFNDSQR | 4.83 (3) | |||
GPAVGIDLGTTYSCVGVFQHGK | 4.65 (3) | |||
SFYPEEVSSMVLTK | 4.05 (2) | |||
SINPDEAVAYGAAVQAAILSGDK | 7.11 (2) | |||
HSPA9 | Stress-70 protein, mitochondrial, a.ka. GRP75 | P38646 | VQQTVQDLFGR | 3.48 (2) |
DAGQISGLNVLR | 3.34 (2) | |||
HSPB4 | AlphaA-crystallin or CRYAA | P02489 | VQDDFVEIHGK | 3.72 (3) |
TVLDSGISEVR | 4.39 (2) | |||
ANXA5 | Annexin A5 | P08758 | LYDAYELK | 2.99 (2) |
VLTEIIASR | 3.45 (2) | |||
GTVTDFPGFDER | 3.82 (2) | |||
M*LVVLLQANR | 3.79 (2) | |||
NFATSLYSM*IK | 3.20 (2) | |||
YM*TISGFQIEETIDR | 5.23 (2) | |||
SIPAYLAETLYYAM*K | 4.20 (2) | |||
GLGTDEESILTLLTSR | 5.61 (2) | |||
ETSGNLEQLLLAVVK | 3.69 (2) | |||
S100A9 | S100 calcium-binding protein A9, a.k.a. calgranulin B | P06702 | VIEHIMEDLDTNADK | 4.91 (2) |
NIETIINTFHQYSVK | 4.98 (2) |
a Asterisk denotes oxidized methionine
b Cross correlation score (XCorr) and charge (z)