Table 3.

Multivariate Analyses of the Association Between Continuous Depressive Symptom Scores with Pro-Inflammatory Cytokine levels

		β	t	SE	p	Model Statistics
						df	F	p	R2	N
IL-1β
Age		0.04	3.21	0.01	0.002
Ethnicity dummy code 1		0.42	1.50	0.28	0.14
Ethnicity dummy code 2		−0.05	−0.14	0.35	0.89
Stage (non-invasive vs. invasive)		0.07	0.26	0.27	0.80
Time since surgery		0.00	−0.83	0.01	0.41
Pain medication use		−0.20	−0.77	0.26	0.44
Fatigue Intensity		−0.01	−0.21	0.07	0.84
Smoking status		−0.71	−1.68	0.42	0.10
HRSD		0.06	2.85	0.02	0.006	9, 71	2.56	0.013	0.25	81
TNF-α
Age		0.04	3.21	0.01	0.002
Ethnicity dummy code 1		0.13	0.56	0.23	0.58
Ethnicity dummy code 2		0.29	0.95	0.31	0.35
Stage (non-invasive vs. invasive)		0.42	1.88	0.22	0.064
Time since surgery		0.00	−0.18	0.00	0.859
Pain medication use		−0.19	−0.86	0.22	0.40
Fatigue Intensity		−0.01	−0.09	0.06	0.93
Smoking status		−0.78	−2.20	0.36	0.031
HRSD		0.06	3.12	0.02	0.003	9, 72	3.02	0.004	0.27	82
IL-6
Age		0.03	1.93	0.02	0.058
Ethnicity dummy code 1		0.45	1.28	0.35	0.21
Ethnicity dummy code 2		1.30	2.91	0.45	0.005
Stage (non-invasive vs. invasive)		0.60	1.83	0.33	0.071
Time since surgery		0.01	1.17	0.01	0.244
Pain medication use		0.23	0.70	0.33	0.49
Fatigue Intensity		−0.01	−0.09	0.08	0.93
Smoking status		−0.42	−0.78	0.54	0.44
HRSD		0.03	0.97	0.03	0.34	9, 75	2.09	0.041	0.20	85

Note. Analyses reported are adjusted for age, ethnicity, stage, time from surgery to study assessment, pain medication use, fatigue intensity, and smoking status.