Fig. 1. Genetic map of the three single nucleotide polymorphism (SNP) of the HMGB1. The three long vertical arrows indicate the locations of the three SNPs. E1 to E5 show the locations of the exons. The black boxes are the protein-coding regions, and boxes including oblique lines are untranslated regions (UTR). rs2249825, rs3742305, and rs1045411 are located in the 5'-UTR, intron 4, and the 3'-UTR, respectively.
