Table 4. Cox Regression Analysis of Variable Factors and HVPG for Mortality in Patients with Decompensated Cirrhosis and Ascites.
| Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95% CI | p value | |
| Sex, male | 1.235 | 0.440-3.467 | 0.211 | |||
| Age, yr | 1.021 | 0.973-1.071 | 0.403 | |||
| Alcohol vs. non-alcohol | 1.547 | 0.509-4.704 | 0.441 | |||
| History of variceal bleeding | 0.602 | 0.226-1.607 | 0.311 | |||
| Use of beta-blocker | 1.369 | 0.513-3.649 | 0.530 | |||
| Platelet count, 103/µL (10 k increase) | 1.006 | 0.943-1.073 | 0.853 | |||
| Albumin, mg/dL (0.1 increase) | 0.909 | 0.829-0.996 | 0.040 | |||
| Bilirubin, mg/dL | 1.182 | 0.953-1.468 | 0.129 | |||
| Prothrombin time, INR (0.1 unit increase) | 1.154 | 1.024-1.301 | 0.019 | 1.146 | 1.011-1.298 | 0.033 |
| Creatinine, mg/dL (0.1 mg/dL increase) | 1.082 | 0.846-1.383 | 0.532 | |||
| Sodium, mEq/L | 0.912 | 0.826-1.007 | 0.067 | |||
| HVPG, mm Hg | 1.081 | 1.010-1.158 | 0.025 | 1.078 | 1.003-1.159 | 0.042 |
| MELD score | 1.132 | 1.023-1.254 | 0.017 | |||
HR, hazard ratio; CI, confidence interval; HVPG, hepatic venous pressure gradient; INR, international normalized ratio; MELD, model for end-stage liver disease.