Table 6. Regression Analysis for Glomerular CD68 Infiltration in a 1:1 Matched Cohort.
Parameter | β coefficient | p value |
---|---|---|
Univariate analysis | ||
Age | 0.003±0.014 | 0.803 |
Smoking dose | 0.006±0.021 | 0.767 |
Hypertension | -0.316±0.364 | 0.388 |
eGFR at time of diagnosis | 0.006±0.007 | 0.409 |
Serum creatinine at time of diagnosis | -0.184±0.283 | 0.518 |
Spot UPCR at time of diagnosis | -0.041±0.157 | 0.797 |
IgA nephropathy, Haas grade | -0.095±0.151 | 0.530 |
Global sclerosis (%) | -0.004±0.009 | 0.648 |
Segmental sclerosis (%) | 0.010±0.014 | 0.504 |
Mesangial α-SMA positive area (%) | -0.357±0.981 | 0.718 |
Tubular atrophy | 0.206±0.235 | 0.382 |
Interstitial fibrosis | -0.111±0.248 | 0.655 |
Arteriolar hyalinosis | 0.195±0.389 | 0.618 |
Arterial fibrointimal thickening | 0.528±0.507 | 0.301 |
Multivariate analysis (%) | ||
Global sclerosis | -0.030±0.011 | 0.008 |
Segmental sclerosis | 0.067±0.019 | 0.001 |
UPCR, urine protein/creatinin ratio; eGFR, estimated glomerular filtration rate; α-SMA, alpha-smooth muscle actin.