Table 2. Selected threshold values of glycosylated hemoglobin and associated data.
Variable | Value | ||||||||
---|---|---|---|---|---|---|---|---|---|
Threshold percentage, % | 5.05 | 5.15 | 5.25 | 5.35 | 5.45 | 5.55 | 5.65 | 5.75 | 5.85 |
No. of patients ≥threshold (TP+FP) | 304 | 268 | 234 | 163 | 116 | 78 | 56 | 40 | 28 |
% of patients ≥threshold | 88.6 | 78.1 | 68.2 | 47.5 | 33.8 | 22.7 | 16.3 | 11.7 | 8.2 |
Sensitivity, % | 98.2 | 95.4 | 93.6 | 87.2 | 73.4 | 50.5 | 42.2 | 31.2 | 23.9 |
Specificity, % | 15.8 | 29.9 | 43.6 | 70.9 | 84.6 | 90.2 | 95.7 | 97.4 | 99.1 |
Positive predictive value, % | 35.2 | 38.8 | 43.6 | 58.3 | 69.0 | 70.5 | 82.1 | 85.0 | 92.9 |
Negative predictive value, % | 94.9 | 93.3 | 93.6 | 92.2 | 87.2 | 79.6 | 78.0 | 75.2 | 73.7 |
False positive rate, % | 84.2 | 70.1 | 56.4 | 29.1 | 15.4 | 9.8 | 4.3 | 2.6 | 0.9 |
False negative rate, % | 1.8 | 4.6 | 6.4 | 12.8 | 26.6 | 49.5 | 57.8 | 68.8 | 76.1 |
Positive likelihood ratio | 1.17 | 1.36 | 1.66 | 3.00 | 4.77 | 5.15 | 9.81 | 12.00 | 26.56 |
Negative likelihood ratio | 0.11 | 0.15 | 0.15 | 0.18 | 0.31 | 0.55 | 0.60 | 0.71 | 0.77 |
TN+FN | 39 | 75 | 109 | 180 | 227 | 265 | 287 | 303 | 315 |
Youden index | 0.140 | 0.253 | 0.372 | 0.581 | 0.580 | 0.407 | 0.379 | 0.286 | 0.230 |
TP, true positive; FP, false positive; TN, true negative; FN, false negative.