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Interaction between omega 3-fatty acids and BDNF that may underlie their cytoprotective actions. Mechanism of cytoprotection may involve: a) prevention of degradation of membrane phospholipids; b) reduction of oxidative stress that helps maintain synaptic plasticity; and c) normalization of levels of BDNF and its downstream effectors synapsin I and CREB, which are important in learning, memory and LTP. This figure is adapted and modified from refs. [89–91]
