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. 2015 Dec 26;2(6):ENEURO.0096-15.2015. doi: 10.1523/ENEURO.0096-15.2015

Figure 8.

Figure 8.

Behavioral effects of the Hoxb1-null mutation in adult mice: linear swimming test and notched beam test. A–C, Linear swimming test. A, B, Examples of alternating hindlimb swimming movements in wild-type mice (A) and synchronous hindlimb swimming movements in Hoxb1-null mice (B). Green and red traces delineate respectively the hindlimb closest to and farthest from the camera. C, Comparison of average number of synchronous hindlimb strokes. D, Comparison of the average time required to swim the total distance of 1 m. E–I, Notched beam test. E, Comparison of average time required to traverse the beam. F, G, Examples of alternating and synchronous locomotor movements in wild-type and Hoxb1-null mice, respectively. H, Comparison of the number of slips made while traversing the beam. I, Comparison of the number of hops made while traversing the beam. Error bars represent SEM. Significant differences with respect to control mice were identified using the PLSD Fisher test: *p < 0.05; **p < 0.01.