Table 3. Influence of covariates on stent failure at 8 weeks and 16 weeks in the Cox multivariate regression model.
Covariate |
8 Weeks |
16 Weeks |
||||||
---|---|---|---|---|---|---|---|---|
Adjusted HR | 95% CI | P value | Adjusted HR | 95% CI | P value | |||
Lower | Upper | Lower | Upper | |||||
Age | ||||||||
<60 Years | 1 | 1 | ||||||
≥60 Years | 0.82 | 0.35 | 1.95 | 0.654 | 0.97 | 0.45 | 2.11 | 0.947 |
Sex | ||||||||
Male | 1 | 1 | ||||||
Female | 0.99 | 0.41 | 2.39 | 0.989 | 0.85 | 0.38 | 1.9 | 0.687 |
Location | ||||||||
Distal antrum | 1 | 1 | ||||||
Pylorus | 0.8 | 0.37 | 1.74 | 0.572 | 0.9 | 0.46 | 1.77 | 0.761 |
Duodenal bulb | 1.56 | 0.4 | 6.12 | 0.523 | 1.51 | 0.45 | 5.12 | 0.508 |
Baseline GOOSS | ||||||||
0 | 1 | 1 | ||||||
1 | 1.23 | 0.53 | 2.88 | 0.632 | 1.01 | 0.49 | 2.08 | 0.616 |
2 | 0 | 0 | — | 0.980 | 0.39 | 0.04 | 4.54 | 0.400 |
Baseline ECOG performance status | ||||||||
1 | 1 | 1 | ||||||
2 | 1.03 | 0.45 | 2.35 | 0.951 | 1.46 | 0.67 | 3.15 | 0.341 |
3 | 0.42 | 0.1 | 1.88 | 0.258 | 0.46 | 0.13 | 1.61 | 0.224 |
Stage | ||||||||
III | 1 | 1 | ||||||
IV | 0 | 0 | — | 0.992 | 2.22 | 0.21 | 23.29 | 0.507 |
Type of stent | ||||||||
Uncovered SEMS | 1 | 1 | ||||||
Wave-covered SEMS | 0.72 | 0.34 | 1.55 | 0.401 | 0.51 | 0.26 | 0.99 | 0.047 |
Length of stent | ||||||||
<12 cm | 1 | 1 | ||||||
≥12 cm | 1.33 | 0.57 | 3.09 | 0.506 | 1.96 | 0.92 | 4.2 | 0.083 |
Post-stenting chemotherapy | ||||||||
Yes | 1 | 1 | ||||||
No | 5.48 | 2.35 | 12.77 | <0.001 | 6.18 | 3.04 | 12.55 | <0.001 |
CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; HR, hazard ratio; SEMS, self-expandable metallic stent.