TABLE 1.
Thrb1-ChIP-Seq analysis in FOXO1-TH up-regulated genes (27 co-regulated genes)
Thrb1-ChIP-Seq analysis in previously known Foxo1 target genes (37) and co-regulated by TH showed two distinct groups of genes. One has Thrb1 binding in the proximal promoter region, and the other does not, yet both gene groups are co-regulated by TH and Foxo1. NA means not applicable.
Serial no. | Gene | Thrb1 binding | No. of peaks |
---|---|---|---|
1 | Cyp17a1 | + | 2 |
2 | Tsku | + | 16 |
3 | Igfbp1 | − | NA |
4 | Ela2a | − | NA |
5 | Pck1 | + | 2 |
6 | Eif4ebp3 | + | 2 |
7 | Dhcr7 | + | 1 |
8 | Pim3 | − | NA |
9 | Rab43 | + | 8 |
10 | Sc5d | − | NA |
11 | Gys2 | + | 1 |
12 | Mgll | + | 91 |
13 | Pdk4 | + | 2 |
14 | Tomm40l | − | NA |
15 | Acacb | + | 4 |
16 | Gdf9 | − | NA |
17 | Ctcfl | − | NA |
18 | Elmod3 | + | 4 |
19 | Slc25a33 | − | NA |
20 | Abcg5 | + | 2 |
21 | Lgals6 | − | NA |
22 | Slc24a6 | + | 111 |
23 | Dusp28 | − | NA |
24 | Sult1a1 | + | 2 |
25 | Klf15 | + | 1 |
26 | Als2cl | + | 78 |
27 | Map1lc3b | − | NA |