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. 2015 Oct 9;291(1):198–214. doi: 10.1074/jbc.M115.668673

TABLE 1.

Thrb1-ChIP-Seq analysis in FOXO1-TH up-regulated genes (27 co-regulated genes)

Thrb1-ChIP-Seq analysis in previously known Foxo1 target genes (37) and co-regulated by TH showed two distinct groups of genes. One has Thrb1 binding in the proximal promoter region, and the other does not, yet both gene groups are co-regulated by TH and Foxo1. NA means not applicable.

Serial no. Gene Thrb1 binding No. of peaks
1 Cyp17a1 + 2
2 Tsku + 16
3 Igfbp1 NA
4 Ela2a NA
5 Pck1 + 2
6 Eif4ebp3 + 2
7 Dhcr7 + 1
8 Pim3 NA
9 Rab43 + 8
10 Sc5d NA
11 Gys2 + 1
12 Mgll + 91
13 Pdk4 + 2
14 Tomm40l NA
15 Acacb + 4
16 Gdf9 NA
17 Ctcfl NA
18 Elmod3 + 4
19 Slc25a33 NA
20 Abcg5 + 2
21 Lgals6 NA
22 Slc24a6 + 111
23 Dusp28 NA
24 Sult1a1 + 2
25 Klf15 + 1
26 Als2cl + 78
27 Map1lc3b NA