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Amelioration of STZ-induced diabetes in Balb/c mice treated with serpin vaccine. Balb/c male pups were intraperitoneal injected on two occasions (days +5 and +10) with 10 μg of mouse serpin B13 diluted in PBS (open, n = 8) or PBS alone (black, n = 7) and injected with a single dose of 100 mg/kg of STZ on day +10 to induce diabetes. Mice were then monitored for blood glucose levels at 1-week intervals, starting on day +17, as indicated.
