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. 2015 Nov 12;291(1):279–290. doi: 10.1074/jbc.M115.691170

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FIGURE 5. — PIAS3 knockdown cells are sensitive to HU, PARP inhibitor, and ATR inhibitor. A, U2OS cells were transfected with control or 2 independent PIAS3 siRNAs, and then treated with HU for 4 days. *, p < 0.05. B, U2OS cells were transfected with control, PIAS3, or BRCA2 siRNA, and then treated with Olaparib for 4 days. *, p < 0.05. C and D, U2OS cells were transfected with control or PIAS3 siRNA, and then treated with VE-21 or AZ20 for 4 days. The cell survival at 1 μm AZ20 and 5 μm VE-821 is shown in D. *, p < 0.05.