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. Author manuscript; available in PMC: 2015 Dec 31.
Published in final edited form as: Curr Med Chem. 2015;22(35):4091–4103. doi: 10.2174/0929867322666150827094015

Fig. (4). Summary of cell engineering achievements using the IWP and IWR classes of Porcn and Tnks inhibitors, respectively.

Fig. (4)

IWP-1, -2, and -4 inhibit Porcn whereas IWR-1 compound inhibits Tnks1 & 2. mES cells=mouse embryonic stem cells; hES cells=human embryonic stem cells; hiPS cells= human induced pluripotent stem cells.