Skip to main content
. Author manuscript; available in PMC: 2015 Dec 31.
Published in final edited form as: Curr Med Chem. 2015;22(35):4091–4103. doi: 10.2174/0929867322666150827094015

Fig. (6). The Porcn active site brings together cytoplasmic palmitoleoyl-CoA and ER luminal Wnt proteins to produce fatty acylated Wnt proteins.

Fig. (6)

Various Porcn inhibitors presumably target the Porcn active site to prevent the formation of a functionally meaningful tri-partite complex.