Table 1. Reference intervals for sex hormones determined with the Advia Centaur system.
Follitropin (mU/mL) | Lutropin (mU/mL) | Estradiol (pg/mL) | Progesterone (ng/mL) | Prolactin (ng/mL) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Median | Lower limit | Upper limit | Median | Lower limit | Upper limit | Median | Lower limit | Upper limit | Median | Lower limit | Upper limit | Median | Lower limit | Upper limit | |
Present study | |||||||||||||||
Male (N = 220) | 3.30 3.11-3.62 |
1.32 1.20-1.46 |
9.18 8.33-10.1 |
3.81 3.59-4.00 |
1.83 1.70-1.96 |
7.65 7.13-8.22 |
21.1 20.2-23.1 |
- | <41.33 7.3-45.6 |
0.42 0.39-0.45 |
- | <0.86 0.76-1.04 |
6.5 5.90-6.90 |
2.73 2.50-2.97 |
15.1 14.1-16.7 |
Follicular phase (N = 139) | 7.58 7.05-7.80 |
4.07 3.77-4.31 |
12.9 12.1-14.0 |
5.00 4.50-5.52 |
2.18 1.97-2.41 |
10.6 9.59-11.7 |
38.1 35.0-41.3 |
- | <82.7 72.0-106 |
0.47 0.43-0.58 |
<1.03 0.93-1.08 |
12.5 11.2-13.6 |
3.88 3.35-4.48 |
40.1 34.7-46.4 |
|
Luteal phase (N = 87) | 4.11 3.40-4.61 |
1.70 1.50-1.92 |
9.46 8.17-10.9 |
4.94 4.10-6.02 |
1.15 0.93-1.44 |
20.9 16.7-25.7 |
109 96.4-119 |
38.9 32.9-46.2 |
296 254-339 |
9.26 8.86-10.7 |
1.14 - |
20.6 - |
16.5 13.5-19.0 |
4.65 3.56-6.15 |
50.9 41.1-68.5 |
Postmenopausal (N = 103) | 87.1 79.6-91.1 |
44.6 40.3-49.8 |
167 150-185 |
32.6 29.6-35.3 |
18.0 16.4-19.8 |
64.2 58.7-70.7 |
9.50 - |
- | < 21.5 15.2-8.1 |
0.17 0.07-0.20 |
- | <0.60 0.42-0.80 |
5.6 5.11-6.10 |
2.64 2.36-2.97 |
11.6 10.5-12.9 |
Manufacturer specifications | |||||||||||||||
Male | 4.5 (N = 117) |
1.4 | 18.1 | 2.8 (N = 59) |
1.5 | 9.3 | 24.8 (N = 100) |
- | 39.8 | 0.54 (N = 80) |
0.28 | 1.22 | 7.0 (N=139) |
2.11 | 17.7 |
Follicular phase | 5.6 (N = 95) |
2.5 | 10.2 | 4.4 (N = 119) |
1.9 | 12.5 | 51.8 (N = 196) |
19.5 | 144.2 | 0.43 (N = 47) |
- | 9.6 (N = 202) |
2.8 | 29.2 | |
Luteal phase | 2.9 (N = 99) |
1.5 | 9.1 | 2.8 (N = 105) |
0.5 | 16.9 | 87.6 (N = 186) |
55.8 | 214.2 | 12.74 (N = 84) |
3.34 | ||||
Postmenopausal | 64.3 (N = 72) |
23 | 116 | 29.7 (N = 35) |
15.9 | 54 | - (N=60) |
- | < 32.2 | 0.27 (N = 46) |
- | 0.73 | 6.9 (N = 104) |
1.8 | 20.3 |
*Reference intervals are presented as 2.5th to 97.5th percentiles. The numbers below the lower or upper limits represent the respective 90% confidence intervals.