Table 1. Clinical information of patients and comparison of morphological and molecular identification methods.
| Patient No. | Age/sex | Specimen | Microscopic morphological ID | Molecular identification | Underlying disease | Diagnosis | Antifungal agent/outcome | ||
|---|---|---|---|---|---|---|---|---|---|
| Sequencing ID | ITS | D1/D2 | |||||||
| Accession No. (identity) | Accession No. (identity) | ||||||||
| 1 | 56/M | Endotracheal | Cunninghamella bertholletiae | C. bertholletiae | ND | FJ345351.1 | Kidney transplant | Pneumonia | Expired |
| 540/540 (100%) | |||||||||
| 2* | Sputum | Lichtheimia sp. | L. corymbifera | EU330179.1 | FJ719444.1 | ||||
| 538/538 (100%) | 462/471 (98%) | ||||||||
| 3 | 52/M | Blood | Lichtheimia sp. | L. corymbifera | HQ285610.1 | ND | DM, liver cirrhosis | ARDS | Expired |
| 702/702 (100%) | |||||||||
| 4 | 69/M | Sputum | Rhizomucor sp. | L. ramosa | JN315007.1 | JN315038.1 | Lung cancer | Lung cancer | Expired |
| 466/468 (99%) | 550/550 (100%) | ||||||||
| 5 | 69/M | Urine | Rhizomucor sp. | L. corymbifera | HQ285610.1 | ND | Diffuse large B cell lymphoma | Diffuse cerebral dysfunction | Expired |
| 702/702 (100%) | |||||||||
| 6 | 53/M | Stool | R/O Rhizomucor sp. | Mucor fragilis | F299225.1 | ND | Liver cirrhosis | Liver transplant work up | |
| 408/408 (100%) | |||||||||
| 7 | 61/M | Sputum | R/O Rhizomucor sp. | R. pusillus | JN315022.1 | ND | Alcoholism | R/O fungal ball | |
| 517/517 (100%) | |||||||||
| 8 | 46/M | Endotracheal | Rhizopus sp. | Rhizopus microsporus | AB381937.1 | AB363776.1 | Liver cirrhosis | Pneumonia | Expired |
| 678/679 (99.9%) | 671/679 (98.8%) | ||||||||
| 9 | 68/M | Nasal | Unidentified Mucorales | Rhizopus microsporus | AY243961.1 | AB250181.1 | DM | Invasive mucormycosis | Amphotericin B/Expired |
| 623/623 (100.0%) | 618/618 (100.0%) | ||||||||
| 10 | 26/M | Endotracheal | R/O Mucor sp. | R. pusillus | AB369914.1 | AF113475.1 | B-ALL | Pneumonia | Expired |
| 610/610 (100%) | 566/566 (100%) | ||||||||
| 11 | 56/M | Stool | Syncephalastrum racemosum | S. racemosum | HM999978.1 | HM849721.1 | HCC | Liver transplant work up | |
| 164/166 (99%) | 422/432 (98%) | ||||||||
| 12 | 56/M | Endotracheal | R/O L corymbifera complex | L. corymbifera | FJ719398.1 | ND | Myelodysplastic syndrome | Pneumonia | Expired |
| 575/575 (100%) | |||||||||
*Clinical information is missing during the procedure of data handling and it was not traceable.
Abbreviations: R/O, rule out; ND, not done; ARDS, acute respiratory distress syndrome; DM, diabetes mellitus; HCC, hepatocellular carcinoma.