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. 2015 Dec 7;112(51):15654–15659. doi: 10.1073/pnas.1511285112

Fig. 1.

Fig. 1.

Deletion of Tmem178 decreases bone mass in basal conditions. (A) Quantitative RT-PCR (Q-RT PCR) analysis of Tmem178 mRNA in whole tissues from WT or PLCγ2−/− mice. (B) Representative microCT images of the proximal femurs of 16-wk-old female WT and Tmem178−/− mice. WT n = 10, Tmem178−/− n = 11. (C) Trabecular bone volume per tissue volume (BV/TV) quantified from microCT shown in B. *P < 0.05. (D) Trabecular thickness (Tb.Th.) from microCT in B. *P < 0.05. (E) Quantification of OC surface per bone surface (Oc.S/B.S.) from TRAP-stained sections. n = 5 per genotype. *P < 0.05. (F) Representative images of TRAP-stained femurs analyzed in E. Arrows indicate OCs.