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. Author manuscript; available in PMC: 2016 Jan 28.
Published in final edited form as: N Engl J Med. 2015 Feb 26;372(9):835–845. doi: 10.1056/NEJMoa1405870

Table 2. Estimated Annual Incidence Rates* of Community-acquired Pneumonia Hospitalization by Year, Site, Age Group, and Pathogen Detected.

Variable Annual no. pneumonia hospitalizations/10,000 children 95% confidence interval

Overall incidence rate 15.7 14.9–16.5
 2010-2011 (year 1) 16.8 15.6-18.0
 2011-2012 (year 2) 14.6 13.5-15.7

Study Site
 Memphis 19.6 18.0–21.3
 Nashville 12.3 11.2–13.4
 Salt Lake City 15.2 13.8–16.5

Age group
 <2 years 62.2 57.6–67.1
 2-4 years 23.8 21.4–26.3
 5-9 years 10.1 8.9–11.3
 10-17 years 4.2 3.6–4.8

Pathogen-specific incidence
 Respiratory Syncytial Virus 4.6 4.3–5.1
 Human Rhinovirus 4.1 3.7–4.4
 Human Metapneumovirus 1.9 1.6–2.1
 Adenovirus 1.6 1.4–1.8
Mycoplasma pneumoniae 1.4 1.2–1.6
 Influenza A/B virus 1.1 0.9–1.3
 Parainfluenza viruses 1-3 0.9 0.8–1.1
 Coronaviruses 0.8 0.7–1.0
Streptococcus pneumoniae 0.5 0.4–0.6
*

Based on 2,212,327 person-years of observation

Annual incidence rates were calculated from July 1, 2010 to June 30, 2011 (year 1) and July 1, 2011 to June 30, 2012 (year 2) and represent the 2012 children with radiographic pneumonia enrolled during that time

Pathogen-specific incidence is calculated for the 1899 children with radiographic pneumonia during the incidence period with at least one specimen available for both bacterial and viral testing. Age-specific pathogen-specific incidence is in Supplementary Table S6.