Table 1.
Patient characteristics at enrollment in a DOTS-Plus treatment program (N = 200)
| Patient characteristic | n (%)* |
|---|---|
| Sex | |
| Male | 165 (83) |
| Female | 35 (18) |
| Age, years [range] | 42 [16–75] |
| Prison status at treatment initiation | |
| Prisoner | 21 (11) |
| Non-prisoner | 179 (90) |
| Initial smear status† | |
| Positive | 139 (70) |
| Negative | 61 (31) |
| Initial culture status† | |
| Positive | 143 (72) |
| Negative | 57 (29) |
| Treatment category and resistance pattern at treatment initiation‡ | |
| New patients without SLD resistance | 42 (21) |
| New patients with SLD resistance | 12 (6) |
| Previously treated with FLDs without SLD resistance | 24 (12) |
| Previously treated with FLDs with SLD resistance | 18 (9) |
| Previously treated with SLDs without SLD resistance | 64 (32) |
| Previously treated with SLDs with SLD resistance | 38 (19) |
| Undetermined | 2 (1) |
| Excessive alcohol or drug use | |
| Yes | 69 (35) |
| No | 131 (66) |
| Cavitary disease | |
| Yes | 171 (86) |
| No | 28 (14) |
| Missing | 1 (1) |
| Bilateral disease | |
| Yes | 126 (63) |
| No | 73 (37) |
| Missing | 1 (1) |
| HIV infection | |
| Yes | 0 |
| No | 198 (99) |
| Missing | 2 (1) |
| Mean time from MDR-TB diagnosis to treatment, days | 446 |
*
Some frequencies may not add up to 100% due to rounding.
†
Initial documented positive culture or smear result within 30 days after enrollment into DOTS-Plus; some patients were being treated in a nonstandardized fashion and were culture- or smear-negative at enrollment.
‡
Data from the first culture and DST obtained after enrollment, or, for those who were culture-negative at enrollment, from the most recent previous positive results.
SLD = second-line drug; FLD = first-line drug; HIV = human immunodeficiency virus; MDR-TB = multidrug-resistant tuberculosis; DST = drug susceptibility testing.