Table 2.
Differential expression of drug transporter genes in EP2 siRNA cells
| Symbol | Fold change | Full name |
|---|---|---|
| ABCC10 | 2.0491 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 |
| ABCC2 | 2.1214 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| SLC19A3 | 32.5594 | Solute carrier family 19 (thiamine transporter), member 3 |
| SLC22A9 | 3.7581 | Solute carrier family 22 (organic anion transporter), member 9 |
| SLC28A1 | 2.2191 | Solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC28A2 | 3.1167 | Solute carrier family 28 (concentrative nucleoside transporter), member 2 |
| SLC7A8 | 3.1932 | Solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| ABCC5 | -6.0419 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ABCG2 | -4.5473 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| SLC16A3 | -2.4538 | Solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC29A1 | -16.1113 | Solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC31A1 | -2.4623 | Solute carrier family 31 (copper transporter), member 1 |
| SLC3A1 | -3.2154 | Solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC7A11 | -2.0705 | Solute carrier family 7 (anionic amino acid transporter light chain, xc-system), member 11 |
| SLCO1B1 | -6.0629 | Solute carrier organic anion transporter family, member 1B1 |
| SLCO2A1 | -3.3519 | Solute carrier organic anion transporter family, member 2A1 |
| SLCO4A1 | -3.3288 | Solute carrier organic anion transporter family, member 4A1 |
RNA was extracted from control-siRNA and EP2-siRNA treated MB-231 cells. Expression levels of 84 genes were analyzed using drug transporter array. Only genes that were upregulated or downregulated by at least 2-fold are listed.