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. 2015 Oct 15;5(11):3422–3435.

Figure 3.

Figure 3

CLR1404 inhibits Akt phosphorylation and activates caspases 3 and 7 in neuroblastoma. A. Western blot of phosphorylated Akt (P-AKT), total Akt (T-AKT) and GAPDH in neuroblastoma cell lines, and calculated densitometric ratio P-AKT/T-AKT. Representative of 3 repeats per cell line. B. Caspase 3 and 7 activity using Caspase-Glo fluorescent substrate in neuroblastoma and normal cells. Means and 95% confidence intervals of two independent experiments are shown. *P<0.05, **P<0.01 and ***P<0.001 of treated versus non-treated cells.