Table 3.
Distribution of the allele frequencies of EZH2 genotypes in controls and oral cancer patients
Variable | Controls (N=1104) n (%) | Patients (N=1152) n (%) | OR (95% CI) | p value |
---|---|---|---|---|
rs6950683 | ||||
T | 748 (67.8%) | 837 (72.7%) | 1.00 | |
C | 356 (32.2%) | 315 (27.3%) | 0.791 (0.660-0.948) | P=0.011* |
rs2302427 | ||||
C | 863 (78.2%) | 912 (79.2%) | 1.00 | |
G | 241 (21.8%) | 240 (20.8%) | 0.942 (0.770-1.153) | P=0.564 |
rs3757441 | ||||
T | 765 (69.3%) | 845 (73.4%) | 1.00 | |
C | 339 (30.7%) | 307 (26.6%) | 0.820 (0.683-0.984) | P=0.033* |
rs41277434 | ||||
A | 1068 (96.7%) | 1115 (96.8%) | 1.00 | |
C | 36 (3.3%) | 37 (3.2%) | 0.984 (0.617-1.570) | P=0.948 |
The odds ratios (ORs) and with their 95% confidence intervals (CIs) were estimated by logistic regression models.
Statistically significant at P < 0.05.