Table 2.

Changes in insulin resistance and FFA suppression after a 12-week exercise training intervention

Variable	Pre-intervention	Post-intervention	% Change	P-value
Peripheral insulin sensitivity
Rd (mg/kg/min)	3.09(0.3)	4.2(0.2)	61.8(15.2)	<0.001
Rd/I (mg/kg/min/μU/ml)	3.03(0.4)	4.9(0.5)	91.2(19.3)	<0.001
Hepatic Glucose Production
Basal Ra (mg/kg/min)	2.7 (0.2)	2.0 (0.3)	−22.9(6.7)	0.01
Clamp Ra (mg/kg/min)	1.5(0.2)	0.83(0.2)	−42.9(12.3)	<0.001
% suppression	46.3(6.0)	57.6(9.1)	27.3(16.1)	0.07
FFA suppression
0 min	0.62(0.02)	0.55(0.02)	−4.0(5.4)	0.15
120 min^	0.17(0.03)	0.13(0.02)	−18.8(8.1)	0.45
% suppression^	74.3(6.2)	82.6(3.6)	11.8(12.0)	0.31

Data reported as Mean(SEM).

^{^}Log-transformed for statistical analysis. Rd = Rate of glucose disposal. I = ambient insulin concentration. Ra = Rate of glucose appearance. FFA = free fatty acid.