Table 1.
ASDa (n=44, 8 female) mean ± SD; range | TDb (n=36, 9 female) mean ± SD; range | p-value | |
---|---|---|---|
Age (years) | 13.2±2.9; 7-18 | 12.8±2.4; 8-17 | .50 |
Nonverbal IQ | 104.5±17.9; 69-140 | 105.4±11.8; 83-129 | .79 |
Verbal IQ | 100.7±20.4; 56-147 | 106.1±12.4; 73-133 | .17 |
Full-Scale IQ | 102.4±18.7; 66-141 | 106.5±11.9; 79-132 | .26 |
SRS Total | 79.7±10.4; 57-100 | 41.9±5.0; 35-52 | <.001 |
ADOS Social | 9.0±3.5; 4-21 | ||
ADOS Communication | 4.3±2.5; 0-13 | ||
ADOS S+C | 12.6±4.9; 1-22 | ||
ADOS Repetitive Behavior | 2.2±1.6; 0-6 | ||
ADI Social | 19.1±5.9; 6-28 | ||
ADI Communication | 15.2±5.9; 2-25 | ||
ADI Repetitive Behavior | 6.5±2.3; 3-12 | ||
DTI Total Motion Index (TMI) | 2.61±4.71; −1.50-18.70 | 0.87±2.53; −1.97-10.88 | 0.07 |
iFC-MRI RMSD | 0.10±0.07; 0.02-0.30 | 0.09±0.07; 0.02-0.30 | 0.46 |
Note: ADI-R = Autism Diagnostic Interview-Revised; ADOS = Autism Diagnostic Observation Schedule; DTI = diffusion tensor imaging; iFC-MRI = intrinsic functional connectivity magnetic resonance imaging; RMSD = root mean square of displacement; S+C = Social+Communication subscale; SRS = Social Responsiveness Scale; TD = typically developing.
IQ scores unavailable for 2 participants; SRS unavailable for 1 participant; ADOS scores unavailable for 4 participants; ADI-R scores unavailable for 2 participants.
SRS scores unavailable for 2 participants.