Table 2. TGFβ increases TGFBR1 (ALK5) and decreases ACVRL1 (ALK1) in human BMSC pellets.
TGFBR1 fold change (Mean ± SD) | ACVRL1 fold change (Mean ± SD) | |||||||
---|---|---|---|---|---|---|---|---|
Day | Donor A1 | P-value | Donor F1 | P-value | Donor A1 | P-value | Donor F1 | P-value |
1 | 2.55 ± 0.39 | 0.010 | 1.98 ± 0.22 | 0.001 | -1.93 ± 0.21 | 0.040 | -2.38 ± 0.30 | 0.001 |
4 | 3.31 ± 0.27 | 0.001 | 2.24 ± 0.12 | ˂0.001 | -3.30 ± 0.51 | 0.003 | -3.32 ± 0.74 | 0.001 |
7 | 7.58 ± 0.26 | ˂0.001 | 2.34 ± 0.19 | 0.005 | -3.98 ± 1.06 | 0.001 | -2.72 ± 0.20 | ˂0.001 |